One of my resolutions for New Years included selling artwork online. So far, ETSY (for the Arts & Crafts crowd) has worked out very well. It's simple to navigate, user friendly, and the fees are reasonable.
I'm also considering setting up an ebay store for auctions since I love, Love, LOVE ebay and the many items I've purchased and sold there. There'll be some teetering back and forth, and after some research -I'll make my decision.